Yes, as soon as you pull the cork or unscrew the cap of a fresh bottle of wine, the bacteria-laden air in the room starts souring the wine. Let us say you have just finished a delightful dinner and there, sitting on your table, is a half-empty, standard-sized wine bottle. Don't just cork the bottle for tomorrow's meal, even if you put it in the refrigerator. Use the popular wine vacuum pump, an inexpensive handheld device that sucks air out of a partially filled wine bottle. Alternatively, pour the liquid into a clean, empty half-sized bottle (saved for this purpose), then cork and store. This will decrease the ullage, the amount of air space lying between the wine and the cork.

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