It was the Princess Han Bao-li that left China to get married with the Sultan (King) of Malacca. The marriage established a kinship and diplomatic relationship between the two nations. At the same time, the famous Admiral Zheng He also stopped by Malacca and Singapore to make his diplomatic visits during his seven epic voyages to the South. These trips attained mutual communication and successfully paved the way for international trade thereafter.

Since then, many Chinese people started trading with or working in Malacca, Penang and Singapore. Some of them even settled down in these coastal cities and as most of these migrants were male, they started marrying the local Malay women which produced a unique culture. Their sons were then called "Baba" and their daughters were called "Nyonya".

Brought up in the cultural background and living habits of the both races, the Malay speaking Babas and Nyonyas in their "sarong" outfits not only keep their Chinese names, but also got accustomed to worshipping their ancestors and eating pork like every Chinese do. In addition, they also inherited the Chinese conventional idea of "men leaving the house to work and women staying at home". Thus, Nyonyas were all culinary experts before marriage and this was exactly the origin of Nyonya cuisine.

Nyonya food is also known as the Straits Chinese food which is an interesting amalgamation of Chinese and Malay dishes thought to have originated from the Peranakan (Straits Chinese) of Malacca. Besides Malacca, Nyonya food is also native to Penang and Singapore. However, over the years, distinct differences have evolved in the Nyonya recipes found in Penang than that in Malacca and Singapore due to the proximity of Malacca and Singapore to Indonesia and Penang to Thailand.